PSME2P5

Across TCGA pan-cancer cohorts, PSME2P5 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated PSME2P5 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher PSME2P5 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PSME2P5 expression acts as an unfavorable survival marker, although some lineages such as SKCM and LUAD show a favorable association.

KICH, SKCM, and ACC are the cancer types where PSME2P5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	OS	Tertile	II,III,IV	0.587	0.976	<.001	72	view →
SKCM	OS	Tertile	All	0.929	0.843	<.001	64	view →
ACC	OS	Quartile	II,III,IV	0.578	0.923	.001	51	view →
STAD	DFS	Tertile	II,III,IV	0.487	0.657	.004	48	view →
KIRC	DFS	Median	All	0.513	0.746	.001	40	view →
UVM	OS	Tertile	III,IV	0.239	0.633	.012	27	view →
ESCA	OS	Tertile	All	0.382	1.000	.002	27	view →
LUAD	DFS	Median	All	0.838	0.747	.002	21	view →
BRCA	DFS	Tertile	IV	0.924	0.549	.010	15	view →
MESO	DFS	Median	II,III,IV	0.644	0.257	.022	12	view →
GBM	DFS	Median	All	0.179	0.290	.007	6	view →
OV	OS	Median	III,IV	0.864	0.808	.020	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

PSME2P5–KICH (OS)

Open the KICH breakdown →