PSME2P4

Across TCGA pan-cancer cohorts, PSME2P4 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated PSME2P4 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher PSME2P4 RNA is associated with better overall survival. In most high-consensus cancer types, elevated PSME2P4 expression acts as an unfavorable survival marker, although some lineages such as UCEC and STAD show a favorable association.

UCEC, STAD, and LIHC are the cancer types where PSME2P4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Quartile	IV	0.814	0.344	.003	68	view →
STAD	OS	Median	IV	0.642	0.179	.001	46	view →
LIHC	DFS	Tertile	All	0.287	0.490	.001	42	view →
ACC	OS	Median	All	0.308	0.791	.001	35	view →
MESO	OS	Median	II,III,IV	0.438	0.655	.003	34	view →
PCPG	OS	Quartile	All	0.896	0.991	.006	22	view →
LUSC	OS	Median	III,IV	0.559	0.737	.009	20	view →
THCA	OS	Quartile	II,III,IV	0.620	1.000	.016	20	view →
LGG	DFS	Quartile	All	0.270	0.537	.002	18	view →
UCS	DFS	Quartile	III,IV	0.767	0.154	.034	10	view →
KIRC	DFS	Median	All	0.849	0.737	.009	10	view →
DLBC	DFS	Tertile	All	0.563	0.937	.009	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

PSME2P4–UCEC (OS)

Open the UCEC breakdown →