PSME1

Across TCGA patient cohorts, PSME1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,591 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PSME1-associated genes across cancer lineages are ETV7, PSME2, and IFNG. Each is linked with PSME1 in more than 9 cancer types. Because this analysis shows association rather than direction, both PSME1-to-partner and partner-to-PSME1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PSME1 versus ETV7 in BRCA, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSME1→partner) and Y-score (partner→PSME1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ETV7 →	+1.183	+0.409	<.001	<.001	3	10
HNSC	PSME2 →	+1.104	+0.386	<.001	<.001	3	10
HNSC	IFNG →	+1.193	+0.397	<.001	<.001	3	10
HNSC	ZBP1 →	+1.413	+0.467	<.001	<.001	3	10
HNSC	IRF1 →	+1.286	+0.432	<.001	<.001	3	10
HNSC	APOL3 →	+1.497	+0.434	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,591 associations by consensus.

PSME1 vs ETV7 — BRCA

Explore this scatter interactively →