PSMD9

Across TCGA patient cohorts, PSMD9 mutation is significantly associated with the total protein of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PSMD9-associated genes across cancer lineages are Annexin-1, TFRC, and 4E-BP1_pT37_T46. Each is linked with PSMD9 in more than 1 cancer types. Because this analysis shows association rather than direction, both PSMD9-to-partner and partner-to-PSMD9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Annexin-1 grouped by PSMD9-low versus PSMD9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMD9→partner) and Y-score (partner→PSMD9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Annexin-1 →	+0.737	+2.827	.015	.035	3	1
UCEC	TFRC →	+0.644	+3.000	.036	.037	3	1
UCEC	4E-BP1_pT37_T46 →	-0.528	-3.000	.014	.036	3	1
UCEC	Myosin-IIa_pS1943 →	+0.280	+3.013	.019	.019	2	1
UCEC	p21 →	+0.323	+3.000	.003	.037	1	1
UCEC	p62 Lck ligand →	+0.399	+3.000	.034	.037	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Annexin-1 by PSMD9 expression — UCEC

Explore this box plot interactively →