Across TCGA pan-cancer cohorts, PSMD7P1 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of PSMD7P1’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where PSMD7P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PSMD7P1 is over-expressed in tumor, although a few such as KIRP and CHOL show the opposite, repressed pattern.
HNSC, COAD, and KIRP are the cancer types where PSMD7P1 tumor–normal differential expression is most reproducible.