PSMD6

Across TCGA cell cohorts, PSMD6 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,670 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible PSMD6-associated GO terms across cancer lineages are tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation, Meiotic sister chromatid cohesion, and Positive regulation of spindle checkpoint. Each is linked with PSMD6 in more than 14 cancer types. Because this analysis shows association rather than direction, both PSMD6-to-partner and partner-to-PSMD6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation grouped by PSMD6-low versus PSMD6-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMD6→partner) and Y-score (partner→PSMD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation →	+0.110	+0.557	.001	.005	3	15
LIVER	Meiotic sister chromatid cohesion →	+0.136	+0.715	.001	.003	3	15
URINARY_TRACT	Positive regulation of spindle checkpoint →	+0.140	+0.882	<.001	<.001	3	14
URINARY_TRACT	Positive regulation of mitotic cell cycle spindle assembly checkpoint →	+0.140	+0.882	<.001	<.001	3	14
KIDNEY	Centromeric sister chromatid cohesion →	+0.148	+0.809	.002	.007	3	14
URINARY_TRACT	Regulation of spindle checkpoint →	+0.126	+0.819	.003	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,670 associations by consensus.

tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation by PSMD6 expression — BONE

Explore this box plot interactively →