PSMD6-AS2

Across TCGA pan-cancer cohorts, PSMD6-AS2 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated PSMD6-AS2 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher PSMD6-AS2 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated PSMD6-AS2 expression acts as an unfavorable survival marker, although some lineages such as HNSC and READ show a favorable association.

HNSC, READ, and LGG are the cancer types where PSMD6-AS2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	All	0.413	0.263	<.001	127	view →
READ	OS	Tertile	II,III,IV	0.911	0.322	.001	33	view →
LGG	OS	Tertile	All	0.734	0.946	<.001	28	view →
LIHC	DFS	Quartile	All	0.412	0.587	.001	27	view →
UCS	DFS	Tertile	IV	0.938	0.304	.017	26	view →
SKCM	DFS	Quartile	All	0.264	0.125	.005	24	view →
OV	OS	Median	IV	0.493	0.757	.004	22	view →
MESO	DFS	Median	All	0.240	0.607	.005	21	view →
BRCA	OS	Median	All	0.973	0.951	.012	21	view →
ACC	DFS	Quartile	IV	0.108	0.621	.002	21	view →
UVM	DFS	Median	III,IV	0.195	0.752	.002	14	view →
THYM	DFS	Median	III,IV	1.000	0.480	.010	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

PSMD6-AS2–HNSC (DFS)

Open the HNSC breakdown →