PSMD5

Across TCGA pan-cancer cohorts, PSMD5 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated PSMD5 data layer compared with 24 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher PSMD5 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated PSMD5 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and HNSC show a favorable association.

CCRCC, HNSC, and GBM are the cancer types where PSMD5 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Tertile	All	1.000	0.494	.001	28	view →
HNSC	OS	Quartile	III,IV	0.957	0.683	.019	7	view →
GBM	DFS	Quartile	All	0.532	0.829	.018	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

PSMD5–CCRCC (OS)

Open the CCRCC breakdown →