PSMD5

Across TCGA cell cohorts, PSMD5 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,957 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PSMD5-associated GO terms across cancer lineages are Proteasome regulatory particle assembly, Positive regulation of chromosome condensation, and Immunoglobulin heavy chain V-D-J recombination. Each is linked with PSMD5 in more than 16 cancer types. Because this analysis shows association rather than direction, both PSMD5-to-partner and partner-to-PSMD5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Proteasome regulatory particle assembly grouped by PSMD5-low versus PSMD5-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMD5→partner) and Y-score (partner→PSMD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Proteasome regulatory particle assembly →	+0.164	+1.120	<.001	<.001	3	17
LUNG_NSCLC_LUSC	Positive regulation of chromosome condensation →	+0.230	+0.855	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Immunoglobulin heavy chain V-D-J recombination →	+0.199	+0.817	<.001	.001	3	13
LUNG_NSCLC_LUSC	Regulation of chromosome condensation →	+0.202	+0.887	.001	.003	2	14
LUNG_NSCLC_LUSC	Establishment of mitotic spindle orientation →	+0.120	+0.904	.001	.002	2	12
LUNG_NSCLC_LUSC	Protein localization to condensed chromosome →	+0.171	+0.929	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,957 associations by consensus.

Proteasome regulatory particle assembly by PSMD5 expression — OVARY

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