PSMD4

Across TCGA patient cohorts, PSMD4 mutation is significantly associated with the RNA expression of many other genes, with 1,894 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PSMD4-associated genes across cancer lineages are OR7E156P, RNU6-379P, and RNU6-694P. Each is linked with PSMD4 in more than 1 cancer types. Because this analysis shows association rather than direction, both PSMD4-to-partner and partner-to-PSMD4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR7E156P grouped by PSMD4-low versus PSMD4-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMD4→partner) and Y-score (partner→PSMD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	OR7E156P →	+0.346	+5.444	.002	<.001	3	2
COAD	RNU6-379P →	+0.805	+3.717	<.001	.008	3	2
COAD	RNU6-694P →	+0.254	+4.308	.003	.009	3	2
COAD	RNU6-927P →	+0.668	+4.602	<.001	.001	3	2
COAD	NTAN1P3 →	+0.167	+3.979	.002	.006	3	2
COAD	MIR4497 →	+0.289	+4.666	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,894 associations by consensus.

OR7E156P by PSMD4 expression — BRCA

Explore this box plot interactively →