PSMD2

Across TCGA patient cohorts, PSMD2 protein abundance is significantly associated with the RNA expression of many other genes, with 16,542 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PSMD2-associated genes across cancer lineages are KPNA2, PGM5, and LMOD1. Each is linked with PSMD2 in more than 7 cancer types. Because this analysis shows association rather than direction, both PSMD2-to-partner and partner-to-PSMD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PSMD2 versus KPNA2 in OV, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMD2→partner) and Y-score (partner→PSMD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	KPNA2 →	+0.939	+0.196	<.001	<.001	3	8
COAD	PGM5 →	-0.983	-0.123	<.001	<.001	3	7
COAD	LMOD1 →	-1.267	-0.139	<.001	<.001	3	7
GBM	TUBA1C →	+0.741	+0.135	.001	.006	3	7
CCRCC	SHE →	-0.803	-0.144	<.001	<.001	3	7
BRCA	HLF →	-1.013	-0.151	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,542 associations by consensus.

PSMD2 vs KPNA2 — OV

Explore this scatter interactively →