PSMD2

Across TCGA patient cohorts, PSMD2 protein abundance is significantly associated with the protein abundance of many other proteins, with 24,044 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PSMD2-associated proteins across cancer lineages are PSMD7, EIF4A1, and EIF4G1. Each is linked with PSMD2 in more than 9 cancer types. Because this analysis shows association rather than direction, both PSMD2-to-partner and partner-to-PSMD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PSMD2 versus PSMD7 in GBM, with a Pearson correlation of 0.82.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMD2→partner) and Y-score (partner→PSMD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PSMD7 →	+0.272	+0.212	<.001	<.001	3	10
HNSC	EIF4A1 →	+0.448	+0.200	<.001	<.001	3	10
LSCC	EIF4G1 →	+0.354	+0.234	<.001	<.001	3	10
LSCC	PSMC1 →	+0.270	+0.309	<.001	<.001	3	10
LSCC	PSMC2 →	+0.225	+0.293	<.001	<.001	3	10
BRCA	PSMC3 →	+0.218	+0.173	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 24,044 associations by consensus.

PSMD2 vs PSMD7 — GBM

Explore this scatter interactively →