PSMD2

Across TCGA cell cohorts, PSMD2 mutation is significantly associated with the RNA expression of many other genes, with 1,018 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PSMD2-associated genes across cancer lineages are SLC2A7, SSX7, and DYNAP. Each is linked with PSMD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PSMD2-to-partner and partner-to-PSMD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC2A7 grouped by PSMD2-low versus PSMD2-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMD2→partner) and Y-score (partner→PSMD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	SLC2A7 →	+0.016	+4.906	<.001	.006	3	1
LUNG_NSCLC_LUAD	SSX7 →	+0.022	+5.662	<.001	.002	3	1
BLOOD_Lymphoma	DYNAP →	+0.071	+4.867	.002	.009	3	1
BLOOD_Lymphoma	KRT33A →	+0.013	+5.643	<.001	.002	3	1
LARGE_INTESTINE	GCAT →	+1.458	+3.169	<.001	.006	3	1
LARGE_INTESTINE	EIF3L →	+0.495	+3.087	.004	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,018 associations by consensus.

SLC2A7 by PSMD2 expression — OESOPHAGUS

Explore this box plot interactively →