PSMD14

Across TCGA patient cohorts, PSMD14 protein abundance is significantly associated with the RNA expression of many other genes, with 12,250 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PSMD14-associated genes across cancer lineages are CEACAM3, ATP8A1, and CSF3R. Each is linked with PSMD14 in more than 4 cancer types. Because this analysis shows association rather than direction, both PSMD14-to-partner and partner-to-PSMD14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PSMD14 versus CEACAM3 in PDAC, with a Pearson correlation of -0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMD14→partner) and Y-score (partner→PSMD14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	CEACAM3 →	-0.605	-0.187	<.001	.004	3	5
HNSC	ATP8A1 →	-0.917	-0.238	<.001	.003	3	5
HNSC	CSF3R →	-1.344	-0.421	<.001	<.001	3	4
GBM	PDE1B →	-0.651	-0.185	.001	<.001	3	4
LSCC	FFAR2 →	-1.301	-0.209	<.001	<.001	3	4
LSCC	PSMC3IP →	+0.620	+0.182	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,250 associations by consensus.

PSMD14 vs CEACAM3 — PDAC

Explore this scatter interactively →