Across TCGA pan-cancer cohorts, PSMD13 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of PSMD13’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where PSMD13 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PSMD13 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.
HNSC, KIRC, and COAD are the cancer types where PSMD13 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PSMD13 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.