Across TCGA patient cohorts, PSMD12 protein abundance is significantly associated with the RNA expression of many other genes, with 11,385 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PSMD12-associated genes across cancer lineages are LDHA, CPED1, and LRRC59. Each is linked with PSMD12 in more than 5 cancer types. Because this analysis shows association rather than direction, both PSMD12-to-partner and partner-to-PSMD12 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMD12→partner) and Y-score (partner→PSMD12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	LDHA →	+0.991	+0.179	<.001	<.001	3	6
COAD	CPED1 →	-0.810	-0.239	<.001	<.001	3	5
HNSC	LRRC59 →	+0.458	+0.114	.008	.002	3	5
LSCC	PFKFB4 →	+1.026	+0.190	<.001	<.001	3	5
LUAD	RAI2 →	-0.612	-0.143	<.001	<.001	3	5
LSCC	FBLN5 →	-0.885	-0.219	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,385 associations by consensus.

Exploration

PSMD12 survival (RNA) · tumor vs normal (RNA) · all PSMD12 data types