Across TCGA patient cohorts, PSMD12 mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PSMD12-associated genes across cancer lineages are PAI-1, ASNS, and mTOR_pS2448. Each is linked with PSMD12 in more than 1 cancer types. Because this analysis shows association rather than direction, both PSMD12-to-partner and partner-to-PSMD12 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMD12→partner) and Y-score (partner→PSMD12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PAI-1 →	+0.300	+2.584	.045	.010	3	2
UCEC	ASNS →	+0.501	+2.999	.001	.035	3	2
UCEC	mTOR_pS2448 →	-0.169	-3.156	.009	.018	3	1
UCEC	Annexin-1 →	+0.593	+3.189	.009	.010	3	1
UCEC	TIGAR →	+0.191	+2.142	.004	.010	3	1
UCEC	ATM →	-0.614	-2.807	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration

PSMD12 survival (RNA) · tumor vs normal (RNA) · all PSMD12 data types