PSMD11

Across TCGA cell cohorts, PSMD11 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,099 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PSMD11-associated GO terms across cancer lineages are DNA replication checkpoint signaling, DNA integrity checkpoint signaling, and DNA replication. Each is linked with PSMD11 in more than 15 cancer types. Because this analysis shows association rather than direction, both PSMD11-to-partner and partner-to-PSMD11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication checkpoint signaling grouped by PSMD11-low versus PSMD11-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMD11→partner) and Y-score (partner→PSMD11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	DNA replication checkpoint signaling →	+0.137	+0.859	<.001	<.001	3	16
BLOOD_Myeloma	DNA integrity checkpoint signaling →	+0.075	+1.138	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	DNA replication →	+0.098	+0.853	.001	.006	3	16
BLOOD_Myeloma	Cell cycle checkpoint signaling →	+0.072	+1.131	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Regulation of DNA-templated DNA replication →	+0.125	+1.110	<.001	<.001	2	16
OESOPHAGUS	rRNA 5'-end processing →	+0.208	+1.450	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,099 associations by consensus.

DNA replication checkpoint signaling by PSMD11 expression — BLOOD_Myeloma

Explore this box plot interactively →