Across TCGA pan-cancer cohorts, PSMD10P2 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of PSMD10P2’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where PSMD10P2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PSMD10P2 is over-expressed in tumor, although a few such as COAD and KICH show the opposite, repressed pattern.
HNSC, LUAD, and LUSC are the cancer types where PSMD10P2 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PSMD10P2 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.