PSMC4

Across TCGA patient cohorts, PSMC4 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,015 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PSMC4-associated proteins across cancer lineages are SUPT5H, MCM6, and TIMM50. Each is linked with PSMC4 in more than 5 cancer types. Because this analysis shows association rather than direction, both PSMC4-to-partner and partner-to-PSMC4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PSMC4 versus SUPT5H in BRCA, with a Pearson correlation of 0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMC4→partner) and Y-score (partner→PSMC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SUPT5H →	+0.409	+0.664	<.001	<.001	3	6
LUAD	MCM6 →	+0.616	+0.328	<.001	<.001	3	6
LSCC	TIMM50 →	+0.493	+0.622	<.001	<.001	3	5
UCEC	TXNDC9 →	+0.214	+1.028	.007	.004	3	5
PDAC	RFC2 →	+0.283	+0.513	.003	.001	3	5
BRCA	RRM2_S20 →	+0.937	+0.536	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,015 associations by consensus.

PSMC4 vs SUPT5H — BRCA

Explore this scatter interactively →