PSMC3IP

Across TCGA pan-cancer cohorts, PSMC3IP Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated PSMC3IP data layer compared with 26 for mass-spec protein and 2 for mass-spec protein.

The strongest signal is observed in thyroid carcinoma (THCA), where higher PSMC3IP Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated PSMC3IP expression acts as an unfavorable survival marker.

THCA are the cancer types where PSMC3IP Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	OS	Median	All	0.277	0.954	<.001	6	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

PSMC3IP–THCA (OS)

Open the THCA breakdown →