PSMC3IP

Across TCGA patient cohorts, PSMC3IP protein abundance is significantly associated with the RNA expression of many other genes, with 12,338 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PSMC3IP-associated genes across cancer lineages are CDCA3, PIMREG, and FANCI. Each is linked with PSMC3IP in more than 4 cancer types. Because this analysis shows association rather than direction, both PSMC3IP-to-partner and partner-to-PSMC3IP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PSMC3IP versus CDCA3 in LUAD, with a Pearson correlation of 0.85.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMC3IP→partner) and Y-score (partner→PSMC3IP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CDCA3 →	+2.118	+1.494	.004	.002	3	5
GBM	PIMREG →	+2.409	+1.405	.002	.007	3	5
GBM	FANCI →	+1.565	+1.447	.004	.007	3	5
LUAD	KIF2C →	+1.944	+1.110	.004	.009	3	4
LUAD	CDC25A →	+1.925	+1.619	.001	.001	3	4
UCEC	MCM2 →	+2.073	+1.292	.002	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,338 associations by consensus.

PSMC3IP vs CDCA3 — LUAD

Explore this scatter interactively →