PSMC3IP

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, PSMC3IP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,511 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PSMC3IP-associated GO terms across cancer lineages are Positive regulation of cell cycle, DNA strand elongation involved in DNA replication, and DNA recombination. Each is linked with PSMC3IP in more than 19 cancer types. Because this analysis shows association rather than direction, both PSMC3IP-to-partner and partner-to-PSMC3IP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cell cycle grouped by PSMC3IP-low versus PSMC3IP-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMC3IP→partner) and Y-score (partner→PSMC3IP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SOFT_TISSUEPositive regulation of cell cycle →+0.068+0.921<.001<.001319
OESOPHAGUSDNA strand elongation involved in DNA replication →+0.217+1.218<.001.002220
BONEDNA recombination →+0.111+1.326<.001.001319
BONEDNA replication checkpoint signaling →+0.237+1.207.001.002319
UPPER_AERODIGESTIVE_TRACTMeiotic cell cycle →+0.085+1.112<.001<.001319
BONECentriole replication →+0.170+1.449<.001<.001319
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,511 associations by consensus.

Positive regulation of cell cycle by PSMC3IP expression — SOFT_TISSUE

Box plot of Positive regulation of cell cycle in PSMC3IP-low vs PSMC3IP-high samples in SOFT_TISSUE.

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