PSMC3IP

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, PSMC3IP mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible PSMC3IP-associated genes across cancer lineages are RESP18. Each is linked with PSMC3IP in more than 1 cancer types. Because this analysis shows association rather than direction, both PSMC3IP-to-partner and partner-to-PSMC3IP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RESP18 grouped by PSMC3IP-low versus PSMC3IP-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMC3IP→partner) and Y-score (partner→PSMC3IP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKINRESP18 →+0.039+5.415<.001.00431
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

RESP18 by PSMC3IP expression — SKIN

Box plot of RESP18 in PSMC3IP-low vs PSMC3IP-high samples in SKIN.

Explore this box plot interactively →

Exploration