PSMC3

Across TCGA cell cohorts, PSMC3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,533 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PSMC3-associated GO terms across cancer lineages are Mitotic spindle elongation, Mitotic spindle midzone assembly, and Spliceosomal tri-snRNP complex assembly. Each is linked with PSMC3 in more than 16 cancer types. Because this analysis shows association rather than direction, both PSMC3-to-partner and partner-to-PSMC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic spindle elongation grouped by PSMC3-low versus PSMC3-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMC3→partner) and Y-score (partner→PSMC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Mitotic spindle elongation →	+0.265	+0.941	<.001	<.001	3	17
SOFT_TISSUE	Mitotic spindle midzone assembly →	+0.265	+0.941	<.001	<.001	3	17
STOMACH	Spliceosomal tri-snRNP complex assembly →	+0.105	+0.515	.001	.002	2	17
BONE	Mitotic chromosome condensation →	+0.148	+0.686	.008	.002	3	15
UPPER_AERODIGESTIVE_TRACT	Cell cycle checkpoint signaling →	+0.082	+1.173	.005	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Regulation of mitotic sister chromatid separation →	+0.137	+0.942	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,533 associations by consensus.

Mitotic spindle elongation by PSMC3 expression — SOFT_TISSUE

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