PSMC1P8

Across TCGA patient cohorts, PSMC1P8 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,012 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PSMC1P8-associated GO terms across cancer lineages are Negative regulation of proteasomal protein catabolic process, Meiotic sister chromatid cohesion, and Establishment of RNA localization. Each is linked with PSMC1P8 in more than 8 cancer types. Because this analysis shows association rather than direction, both PSMC1P8-to-partner and partner-to-PSMC1P8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of proteasomal protein catabolic process grouped by PSMC1P8-low versus PSMC1P8-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMC1P8→partner) and Y-score (partner→PSMC1P8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of proteasomal protein catabolic process →	+0.065	+0.050	<.001	.002	3	9
STAD	Meiotic sister chromatid cohesion →	+0.060	+0.053	<.001	<.001	3	8
STAD	Establishment of RNA localization →	+0.075	+0.054	<.001	<.001	3	8
STAD	Nucleobase-containing compound transport →	+0.070	+0.044	<.001	.005	3	8
ESCA	DNA integrity checkpoint signaling →	+0.062	+0.068	.002	.001	3	8
STAD	Ribosomal small subunit biogenesis →	+0.088	+0.055	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,012 associations by consensus.

Negative regulation of proteasomal protein catabolic process by PSMC1P8 expression — STAD

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