PSMC1P7

Across TCGA pan-cancer cohorts, PSMC1P7 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of PSMC1P7’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where PSMC1P7 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PSMC1P7 is over-expressed in tumor, although a few such as ESCA show the opposite, repressed pattern.

HNSC, LUAD, and BRCA are the cancer types where PSMC1P7 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PSMC1P7 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	IV	+0.081	.021	4	view →
LUAD	All	All	+0.036	.001	4	view →
BRCA	Female	II,III,IV	+0.041	.028	2	view →
ESCA	Female	All	−0.240	.007	1	view →
LUSC	All	All	+0.095	.048	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

PSMC1P7–HNSC

Open the HNSC breakdown →