PSMC1P6

Across TCGA pan-cancer cohorts, PSMC1P6 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of PSMC1P6’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where PSMC1P6 RNA is repressed in tumor relative to normal tissue. In most cancer types PSMC1P6 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

KIRC are the cancer types where PSMC1P6 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PSMC1P6 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	III,IV	−0.006	.022	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

PSMC1P6–KIRC

Open the KIRC breakdown →