PSMC1P4

Across TCGA pan-cancer cohorts, PSMC1P4 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated PSMC1P4 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher PSMC1P4 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PSMC1P4 expression acts as an unfavorable survival marker, although some lineages such as DLBC and UCS show a favorable association.

KIRP, MESO, and COAD are the cancer types where PSMC1P4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Tertile	All	0.473	0.645	<.001	101	view →
MESO	OS	Median	All	0.273	0.473	<.001	69	view →
COAD	OS	Tertile	II,III,IV	0.650	0.832	.008	65	view →
KIRC	DFS	Median	II,III,IV	0.416	0.602	.001	64	view →
KICH	OS	Tertile	III,IV	0.125	0.815	<.001	60	view →
LGG	DFS	Quartile	All	0.546	0.770	<.001	22	view →
STAD	DFS	Quartile	III,IV	0.489	0.688	.012	20	view →
ACC	OS	Tertile	III,IV	0.312	0.801	.006	20	view →
PAAD	DFS	Tertile	III,IV	0.118	0.734	.014	18	view →
DLBC	OS	Median	IV	1.000	0.417	.013	15	view →
UVM	DFS	Tertile	II,III,IV	0.508	0.789	.021	15	view →
CHOL	OS	Tertile	III,IV	0.267	0.917	.038	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

PSMC1P4–KIRP (DFS)

Open the KIRP breakdown →