Across TCGA pan-cancer cohorts, PSMC1P12 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of PSMC1P12’s most consistent transcriptional readouts.

The strongest signal is observed in prostate adenocarcinoma (PRAD), where PSMC1P12 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PSMC1P12 is over-expressed in tumor, although a few such as KIRP show the opposite, repressed pattern.

PRAD, HNSC, and KIRP are the cancer types where PSMC1P12 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PSMC1P12 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
PRAD	All	All	+0.035	.038	2	view →
HNSC	All	All	+0.045	.043	1	view →
KIRP	Male	All	−0.032	.026	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: PSMC1P12 RNA expression & survival · all PSMC1P12 data types