PSMB9

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, PSMB9 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,669 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible PSMB9-associated GO terms across cancer lineages are Antigen processing and presentation of endogenous antigen, Antigen processing and presentation of endogenous peptide antigen via MHC class I, and Antigen processing and presentation of peptide antigen via MHC class I. Each is linked with PSMB9 in more than 19 cancer types. Because this analysis shows association rather than direction, both PSMB9-to-partner and partner-to-PSMB9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Antigen processing and presentation of endogenous antigen grouped by PSMB9-low versus PSMB9-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMB9→partner) and Y-score (partner→PSMB9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UPPER_AERODIGESTIVE_TRACTAntigen processing and presentation of endogenous antigen →+0.368+2.801<.001<.001320
BREASTAntigen processing and presentation of endogenous peptide antigen via MHC class I →+0.313+3.422<.001<.001320
UPPER_AERODIGESTIVE_TRACTAntigen processing and presentation of peptide antigen via MHC class I →+0.256+2.826<.001<.001320
UPPER_AERODIGESTIVE_TRACTAntigen processing and presentation of endogenous peptide antigen →+0.355+2.666<.001<.001320
BREASTAntigen processing and presentation of peptide antigen via MHC class Ib →+0.295+2.294<.001<.001320
BLOOD_MyelomaAntigen processing and presentation of peptide antigen →+0.172+1.205.001.001320
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,669 associations by consensus.

Antigen processing and presentation of endogenous antigen by PSMB9 expression — UPPER_AERODIGESTIVE_TRACT

Box plot of Antigen processing and presentation of endogenous antigen in PSMB9-low vs PSMB9-high samples in UPPER_AERODIGESTIVE_TRACT.

Explore this box plot interactively →

Exploration