Across TCGA patient cohorts, PSMB8 protein abundance is significantly associated with the RNA expression of many other genes, with 15,429 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PSMB8-associated genes across cancer lineages are APOL6, PSMB9, and BTN3A1. Each is linked with PSMB8 in more than 8 cancer types. Because this analysis shows association rather than direction, both PSMB8-to-partner and partner-to-PSMB8 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMB8→partner) and Y-score (partner→PSMB8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	APOL6 →	+1.016	+0.445	<.001	<.001	3	9
BRCA	PSMB9 →	+1.393	+0.465	<.001	<.001	3	9
UCEC	BTN3A1 →	+0.865	+0.455	<.001	<.001	3	9
BRCA	ETV7 →	+1.506	+0.471	<.001	<.001	3	8
HNSC	APOL1 →	+1.771	+0.413	<.001	<.001	3	8
HNSC	OAS2 →	+1.552	+0.461	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,429 associations by consensus.

Exploration

PSMB8 survival (RNA) · tumor vs normal (RNA) · all PSMB8 data types