PSMB8

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, PSMB8 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,158 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PSMB8-associated GO terms across cancer lineages are Antigen processing and presentation of peptide antigen, Antigen processing and presentation of endogenous peptide antigen via MHC class I, and Antigen processing and presentation of endogenous peptide antigen. Each is linked with PSMB8 in more than 19 cancer types. Because this analysis shows association rather than direction, both PSMB8-to-partner and partner-to-PSMB8 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMB8→partner) and Y-score (partner→PSMB8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BONEAntigen processing and presentation of peptide antigen →+0.185+4.210<.001<.001320
LIVERAntigen processing and presentation of endogenous peptide antigen via MHC class I →+0.300+3.397.001.007320
LIVERAntigen processing and presentation of endogenous peptide antigen →+0.287+3.374.001.008320
SOFT_TISSUEAntigen processing and presentation of peptide antigen via MHC class I →+0.225+4.694<.001<.001319
BREASTAntigen processing and presentation of endogenous antigen →+0.293+3.322<.001<.001319
BONEAntigen processing and presentation →+0.187+4.410<.001<.001318
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,158 associations by consensus.

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