PSMB4

Across TCGA patient cohorts, PSMB4 protein abundance is significantly associated with the RNA expression of many other genes, with 7,770 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PSMB4-associated genes across cancer lineages are CSPP1, RMND5A, and TMEM67. Each is linked with PSMB4 in more than 4 cancer types. Because this analysis shows association rather than direction, both PSMB4-to-partner and partner-to-PSMB4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PSMB4 versus CSPP1 in OV, with a Pearson correlation of -0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMB4→partner) and Y-score (partner→PSMB4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CSPP1 →	-0.508	-0.150	.005	.003	2	5
LSCC	RMND5A →	-0.648	-0.099	<.001	.006	3	4
LSCC	TMEM67 →	-0.620	-0.135	<.001	<.001	3	4
BRCA	FBXL2 →	-0.660	-0.225	<.001	<.001	3	4
LSCC	SINHCAF →	-0.735	-0.121	<.001	.001	3	4
LSCC	SNRPD3 →	-0.747	-0.201	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,770 associations by consensus.

PSMB4 vs CSPP1 — OV

Explore this scatter interactively →