PSMB3

Across TCGA cell cohorts, PSMB3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,435 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PSMB3-associated GO terms across cancer lineages are Dihydrofolate metabolic process, Flagellated sperm motility, and Sperm motility. Each is linked with PSMB3 in more than 12 cancer types. Because this analysis shows association rather than direction, both PSMB3-to-partner and partner-to-PSMB3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Dihydrofolate metabolic process grouped by PSMB3-low versus PSMB3-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMB3→partner) and Y-score (partner→PSMB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Dihydrofolate metabolic process →	+0.249	+1.083	<.001	<.001	3	13
SOFT_TISSUE	Flagellated sperm motility →	+0.094	+0.564	<.001	.007	3	13
SOFT_TISSUE	Sperm motility →	+0.094	+0.564	<.001	.007	3	13
STOMACH	Regulation of androgen receptor signaling pathway →	-0.076	-0.715	.004	.004	3	12
OVARY	Cilium movement involved in cell motility →	+0.078	+0.787	<.001	<.001	3	10
BLOOD_Myeloma	DNA replication initiation →	+0.158	+0.804	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,435 associations by consensus.

Dihydrofolate metabolic process by PSMB3 expression — URINARY_TRACT

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