Across TCGA patient cohorts, PSMB11 mutation is significantly associated with the RNA expression of many other genes, with 1,742 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PSMB11-associated genes across cancer lineages are RPS27P20, GLRXP1, and MIR627. Each is linked with PSMB11 in more than 2 cancer types. Because this analysis shows association rather than direction, both PSMB11-to-partner and partner-to-PSMB11 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMB11→partner) and Y-score (partner→PSMB11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RPS27P20 →	+0.157	+4.601	.002	.004	3	3
CESC	GLRXP1 →	+0.084	+4.669	.001	.007	3	3
SKCM	MIR627 →	+0.169	+3.291	<.001	.006	3	3
CESC	RN7SL607P →	+0.177	+4.503	.001	.005	3	2
CESC	HMGN2P9 →	+0.178	+4.601	.002	.004	3	2
STAD	RNA5SP325 →	+0.580	+3.878	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,742 associations by consensus.

Exploration

PSMB11 survival (RNA) · tumor vs normal (RNA) · all PSMB11 data types