Across TCGA patient cohorts, PSMB10 protein abundance is significantly associated with the RNA expression of many other genes, with 18,240 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PSMB10-associated genes across cancer lineages are APOBEC3H, ETV7, and GRAP2. Each is linked with PSMB10 in more than 9 cancer types. Because this analysis shows association rather than direction, both PSMB10-to-partner and partner-to-PSMB10 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMB10→partner) and Y-score (partner→PSMB10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	APOBEC3H →	+0.856	+0.452	<.001	<.001	3	10
OV	ETV7 →	+1.702	+0.608	<.001	<.001	3	10
HNSC	GRAP2 →	+0.944	+0.518	<.001	<.001	3	10
BRCA	IL2RB →	+1.197	+0.464	<.001	<.001	3	10
UCEC	GZMH →	+1.498	+0.590	<.001	<.001	3	10
OV	PSME2 →	+0.867	+0.507	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,240 associations by consensus.

Exploration

PSMB10 survival (RNA) · tumor vs normal (RNA) · all PSMB10 data types