Across TCGA patient cohorts, PSMB10 mutation is significantly associated with the RNA expression of many other genes, with 240 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PSMB10-associated genes across cancer lineages are RNU6-910P, RN7SKP91, and RNU2-61P. Each is linked with PSMB10 in more than 1 cancer types. Because this analysis shows association rather than direction, both PSMB10-to-partner and partner-to-PSMB10 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMB10→partner) and Y-score (partner→PSMB10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-910P →	+0.374	+2.717	<.001	.006	3	2
UCEC	RN7SKP91 →	+0.277	+2.599	<.001	.009	3	2
UCEC	RNU2-61P →	+0.456	+4.136	<.001	<.001	3	2
UCEC	RNA5SP436 →	+0.490	+3.352	<.001	.004	3	2
SKCM	LCN1P2 →	+0.221	+5.513	<.001	.004	3	2
HNSC	RNU5E-8P →	+0.324	+6.221	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 240 associations by consensus.

Exploration

PSMB10 survival (RNA) · tumor vs normal (RNA) · all PSMB10 data types