PSMB10

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, PSMB10 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,217 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PSMB10-associated GO terms across cancer lineages are Regulation of regulatory T cell differentiation, Antigen processing and presentation of peptide antigen via MHC class I, and CD8-positive, alpha-beta T cell homeostasis. Each is linked with PSMB10 in more than 15 cancer types. Because this analysis shows association rather than direction, both PSMB10-to-partner and partner-to-PSMB10 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMB10→partner) and Y-score (partner→PSMB10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
URINARY_TRACTRegulation of regulatory T cell differentiation →+0.164+1.253.005.001316
UPPER_AERODIGESTIVE_TRACTAntigen processing and presentation of peptide antigen via MHC class I →+0.206+1.403<.001.002315
URINARY_TRACTCD8-positive, alpha-beta T cell homeostasis →+0.207+1.287<.001<.001315
URINARY_TRACTCD8-positive, alpha-beta T cell differentiation →+0.181+1.418<.001<.001315
KIDNEYThymic T cell selection →+0.116+0.859.003<.001315
URINARY_TRACTNegative regulation of regulatory T cell differentiation →+0.237+1.421<.001<.001315
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,217 associations by consensus.

Exploration