PSMB1

Across TCGA patient cohorts, PSMB1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,735 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PSMB1-associated genes across cancer lineages are PSME2, PSMB9, and TPTEP1. Each is linked with PSMB1 in more than 5 cancer types. Because this analysis shows association rather than direction, both PSMB1-to-partner and partner-to-PSMB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PSMB1 versus PSME2 in UCEC, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMB1→partner) and Y-score (partner→PSMB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PSME2 →	+0.968	+0.170	<.001	.001	3	6
BRCA	PSMB9 →	+1.074	+0.260	.001	<.001	3	6
LUAD	TPTEP1 →	-1.088	-0.154	.002	<.001	3	4
BRCA	ETV7 →	+0.892	+0.158	<.001	<.001	3	4
LUAD	PSMA6 →	+0.353	+0.093	.002	.001	3	4
BRCA	IL21R →	+0.633	+0.221	.005	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,735 associations by consensus.

PSMB1 vs PSME2 — UCEC

Explore this scatter interactively →