PSMB1

Across TCGA patient cohorts, PSMB1 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PSMB1-associated genes across cancer lineages are Hepatocytes, Myocytes, and Pericytes. Each is linked with PSMB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PSMB1-to-partner and partner-to-PSMB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Hepatocytes grouped by PSMB1-low versus PSMB1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMB1→partner) and Y-score (partner→PSMB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Hepatocytes →	+0.016	+2.899	.013	.040	3	1
UCEC	Myocytes →	+0.045	+2.850	.023	.035	3	1
UCEC	Pericytes →	+0.038	+2.113	.018	.044	3	1
UCEC	CMP →	+0.038	+2.818	.042	.037	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Hepatocytes by PSMB1 expression — UCEC

Explore this box plot interactively →