PSMA7

Across TCGA pan-cancer cohorts, PSMA7 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated PSMA7 data layer compared with 27 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher PSMA7 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated PSMA7 expression acts as an unfavorable survival marker.

BLCA and CESC are the cancer types where PSMA7 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Median	III,IV	0.139	0.657	<.001	33	view →
CESC	OS	Median	All	0.277	0.798	.012	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

PSMA7–BLCA (OS)

Open the BLCA breakdown →