PSMA5

Across TCGA patient cohorts, PSMA5 mutation is significantly associated with the RNA expression of many other genes, with 40 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PSMA5-associated genes across cancer lineages are RNU6-1213P, MIR544A, and MTND1P16. Each is linked with PSMA5 in more than 1 cancer types. Because this analysis shows association rather than direction, both PSMA5-to-partner and partner-to-PSMA5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1213P grouped by PSMA5-low versus PSMA5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMA5→partner) and Y-score (partner→PSMA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-1213P →	+0.332	+4.292	<.001	.006	3	2
HNSC	MIR544A →	+0.318	+7.954	<.001	.008	3	1
SKCM	MTND1P16 →	+0.037	+4.385	<.001	.008	3	1
UCEC	FEZF1 →	+0.733	+3.523	.004	.007	3	1
UCEC	IL9 →	+0.118	+3.384	.004	.002	3	1
UCEC	SMIM28 →	+0.444	+3.955	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

RNU6-1213P by PSMA5 expression — UCEC

Explore this box plot interactively →