PSMA5

Across TCGA cell cohorts, PSMA5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,200 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PSMA5-associated GO terms across cancer lineages are Protection from non-homologous end joining at telomere, Telomeric 3' overhang formation, and Zinc ion import into Golgi lumen. Each is linked with PSMA5 in more than 14 cancer types. Because this analysis shows association rather than direction, both PSMA5-to-partner and partner-to-PSMA5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protection from non-homologous end joining at telomere grouped by PSMA5-low versus PSMA5-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMA5→partner) and Y-score (partner→PSMA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Protection from non-homologous end joining at telomere →	+0.129	+1.098	<.001	<.001	3	15
LUNG_NSCLC_LUAD	Telomeric 3' overhang formation →	+0.112	+0.677	<.001	.001	3	14
KIDNEY	Zinc ion import into Golgi lumen →	+0.110	+0.791	<.001	<.001	3	13
URINARY_TRACT	Positive regulation of mRNA splicing, via spliceosome →	+0.144	+0.814	<.001	.005	3	12
BLOOD_Myeloma	Positive regulation of mRNA processing →	+0.135	+1.356	<.001	<.001	3	11
BLOOD_Myeloma	DNA replication initiation →	+0.184	+1.365	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,200 associations by consensus.

Protection from non-homologous end joining at telomere by PSMA5 expression — BREAST

Explore this box plot interactively →