PSMA3

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PSMA3 protein abundance is significantly associated with the RNA expression of many other genes, with 13,302 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PSMA3-associated genes across cancer lineages are PSME2, PSMB9, and PWWP3B. Each is linked with PSMA3 in more than 4 cancer types. Because this analysis shows association rather than direction, both PSMA3-to-partner and partner-to-PSMA3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PSMA3 versus PSME2 in OV, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMA3→partner) and Y-score (partner→PSMA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVPSME2 →+0.677+0.201.001<.00135
OVPSMB9 →+0.990+0.163.001.00135
LUADPWWP3B →-1.045-0.109.005.00634
GBMCSDC2 →-0.709-0.094<.001.00934
OVNDRG3 →-0.688-0.203<.001<.00134
OVMIR99AHG →-0.677-0.214<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,302 associations by consensus.

PSMA3 vs PSME2 — OV

Per-sample scatter of PSMA3 vs PSME2 in OV (Pearson r = 0.34).

Explore this scatter interactively →

Exploration