PSMA3

Across TCGA patient cohorts, PSMA3 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PSMA3-associated genes across cancer lineages are Basophils, Endothelial cells, and Erythrocytes. Each is linked with PSMA3 in more than 1 cancer types. Because this analysis shows association rather than direction, both PSMA3-to-partner and partner-to-PSMA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Basophils grouped by PSMA3-low versus PSMA3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMA3→partner) and Y-score (partner→PSMA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Basophils →	+0.157	+3.169	.034	.019	3	2
UCEC	Endothelial cells →	-0.039	-2.072	.019	.019	3	1
UCEC	Erythrocytes →	+0.032	+2.807	.003	.003	2	2
UCEC	lymphatic Endothelial cells →	-0.022	-2.419	.035	.020	3	1
UCEC	mv Endothelial cells →	-0.026	-3.321	.012	.010	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Basophils by PSMA3 expression — UCEC

Explore this box plot interactively →