PSMA3

Across TCGA cell cohorts, PSMA3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,040 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible PSMA3-associated GO terms across cancer lineages are Mitochondrial tRNA methylation, Protein localization to condensed chromosome, and Positive regulation of toll-like receptor signaling pathway. Each is linked with PSMA3 in more than 13 cancer types. Because this analysis shows association rather than direction, both PSMA3-to-partner and partner-to-PSMA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial tRNA methylation grouped by PSMA3-low versus PSMA3-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMA3→partner) and Y-score (partner→PSMA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Mitochondrial tRNA methylation →	+0.113	+1.195	<.001	<.001	3	14
OESOPHAGUS	Protein localization to condensed chromosome →	+0.177	+0.820	<.001	.001	3	12
LARGE_INTESTINE	Positive regulation of toll-like receptor signaling pathway →	-0.127	-0.707	<.001	<.001	3	11
BONE	tRNA 5'-leader removal →	+0.113	+0.645	.004	.005	3	11
BONE	Mitochondrial tRNA 5'-end processing →	+0.161	+1.110	<.001	<.001	3	11
CNS	Positive regulation of endosome organization →	-0.070	-0.513	.002	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,040 associations by consensus.

Mitochondrial tRNA methylation by PSMA3 expression — BLOOD_Myeloma

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