Q-omics provides the consensus-scored PSMA1P1 profile across patient tissues and cancer cell-line models. PSMA1P1 expression is associated with patient survival in 14 of 34 cancer types, with the highest sampling consensus in BRCA. Among the 18 cancer types available for tumor–normal comparison, PSMA1P1 is differentially expressed in 9, with the highest sampling consensus in COAD. Additionally, PSMA1P1 RNA expression shows 10,948 significant gene co-expression associations, with the highest sampling consensus in DLBC. Together, these results highlight BRCA, COAD, and DLBC as cancer lineages where PSMA1P1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for PSMA1P1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes PSMA1P1 survival associations across molecular data types. PSMA1P1 RNA expression shows survival associations in the most cancer types (14). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible PSMA1P1 RNA expression–survival associations across cancer types. High PSMA1P1 expression shows unfavorable associations in KICH, COAD, ACC and CESC, but favorable associations in BRCA and KIRC. The BRCA Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify BRCA as the clearest survival context for PSMA1P1 RNA expression.
This table summarizes PSMA1P1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 9. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for PSMA1P1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. PSMA1P1 shows higher tumor expression in COAD, HNSC, KIRC, CHOL, LUAD and BRCA. The COAD box plot shows higher PSMA1P1 RNA expression in tumor versus normal tissue (log2 FC = +0.220, t-test p < 0.001).
This table shows molecular features associated with PSMA1P1 in patient tissues and cancer cell lines. In patient samples, PSMA1P1 shows the broadest associations at the RNA and protein expression levels, with DLBC recurring as the lineage with the largest associated feature set.
