PSMA1

Across TCGA cell cohorts, PSMA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,472 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PSMA1-associated GO terms across cancer lineages are Protein histidyl modification to diphthamide, Peptidyl-histidine modification, and Translation reinitiation. Each is linked with PSMA1 in more than 9 cancer types. Because this analysis shows association rather than direction, both PSMA1-to-partner and partner-to-PSMA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein histidyl modification to diphthamide grouped by PSMA1-low versus PSMA1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMA1→partner) and Y-score (partner→PSMA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Protein histidyl modification to diphthamide →	+0.101	+0.606	.003	.009	3	10
STOMACH	Peptidyl-histidine modification →	+0.101	+0.606	.003	.009	3	10
UPPER_AERODIGESTIVE_TRACT	Translation reinitiation →	+0.060	+0.592	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Nucleolus organization →	+0.103	+0.596	.001	.008	3	10
LARGE_INTESTINE	Deoxyribonucleotide biosynthetic process →	+0.111	+0.598	.001	<.001	3	10
URINARY_TRACT	Regulation of mitotic sister chromatid separation →	+0.158	+0.678	.003	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,472 associations by consensus.

Protein histidyl modification to diphthamide by PSMA1 expression — STOMACH

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