PSKH2

Across TCGA pan-cancer cohorts, PSKH2 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated PSKH2 data layer compared with 18 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher PSKH2 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated PSKH2 expression acts as an unfavorable survival marker, although some lineages such as SKCM show a favorable association.

UCEC, LGG, and LIHC are the cancer types where PSKH2 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
LGG	OS	Median	All	0.307	0.799	.012	3	view →
LIHC	OS	Median	All	0.144	0.704	.016	3	view →
SKCM	DFS	Median	II,III,IV	0.791	0.540	.019	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

PSKH2–UCEC (OS)

Open the UCEC breakdown →